Since response seems to have helped others, perhaps you might have some idea what's going on with my Epson Perfection 1250.
It worked fine with Lion for months, producing hundreds of scans, but suddenly the connection just blew, for no reason that I can discern. Now I get the dreaded grey circle with a line through it. I've tried unplugging/replugging, rebooting, setting it up again via Print & Scan, and nothing.
I don't think the scanner is kaput, as it still works with other computers.
I'd really prefer not to have to buy another scanner, as I really liked the interface on my old one, and all I use it for is documents, so I don't need all the fancy features of the new ones.
Any thoughts?