I think the real problem here is that, for some reason, iTunes isn't properly handling an iphone that has left the wifi network. I can link up my phone, and sync or not as I wish, and there are no problems. There are no problems for hours. Should I walk out the door and take my phone out of range of my wifi, this error pops up.
The secondary issue is that the message seems to queue up. When I get back within wifi range, the dialog has appeared. Depending on the length of time I have been away, more or less messages will appear. This indicates that it isn't a fresh popup each time, but popups that have queued up every x minutes. Since I have just arrived home after 48 hours away from home, I have quite a few of these things to click away now.
This seems to be a simple matter to fix in iTunes by apple. Never pop the dialog up at all. Simply place a yellow exclamation point (Use some color, Apple. It's okay) next to that device, or allow it to dissapear once from the list and popup the message corresponding to this dissapearance. Because iTunes doesn't seem to be releasing the device when it goes out of range, perhaps there should be some developer attention to the handling of this.
It's a very frustrating thorn on an otherwise lovely rose, but that sucker just keeps on sticking.