I had all the problems stated above, while trying to scan with Image Capture. I got nothing but the "the scan operation is cancelled", after multiple tries. I called Epson. They said there was no driver that would work with OS X 10.8.4 for this scanner, and suggested that I call Apple. Apple said there was nothing they could do, and that I should call Epson. I followed the advise someone gave above, and downloaded EPSON Scan 3.8.0. The Epson software didn't work. It didn't seem to be able to pick up the 1640 XL. But, suddenly, I could preview with Image Capture. It was progress, but wouldn't work past the Overview step. The Scan button was "greyed out", not allowing me to proceed. I then tried importing through Photoshop. It works! Go to File/Import/Images from Device and you will get beautiful scans. Good luck, everyone.