For the entire first week that I had my MacBook Pro, there was no hiss sound from the left speaker. Then one week later, (about 2 weeks ago), right after an automatic Firmware update (not software update), occurred (after I okayed it), I noticed the hissing sound immediately! If you plug your headphones or any audio or optical cable (a dummy plug, for all that matters), into the audio out jack, you hear the audio amp pop as it disconnects the amplifier that drives the speakers, and the hiss is gone! Now, the good news is that the noise is NON-EXISTANT in the headphones!
I believe that the last MacBook Pro firmware update did something with the signal to noise ratio in the amplifier that drives the speakers, assuming that it would have to be after the pre-amp section since you hear a pop as you push the plug into the jack, and the fact that the noise is totally gone in the headphones.) Until they come out with another firmware update, I'll just use either the optical out (same as headphone out, only digital optical) or my external iMic ($35.00) USB D/A for audio. If you're mobile, in the library, you should be using your headphones anyway, and should not hear the loud hiss that I'm describing.
I hope this helps!!!
--M
MacBook Pro 17 Mac OS X (10.4.7) 2gig DDR2 SDRAM