joel77-
There are an incredible number of variables. Signal strength can vary in distances as short as a few feet, and different antenna designs in different devices can produce very different results for signal-to-noise ratio.
The first thing to get right is to reduce direct competition for the channel you are using (or use a different channel until you have little or no competition).
Once you are not fighting with your neighbors' Routers, you can move your Router and your computer around to get the strongest signal and not too much noise so that you can operate without issues. Trying to optimize placement without first reducing competition is an exercise in futility.
More subtle issues can come from moving much larger amounts of data through your computer than your other devices.