Have a Patriot 64GB stick and after my new MacBook Pro Retina decided to tell me I had removed it too soon. (no, I hadn't) things got wonky with the stick so I formatted it using Disk Utility and Tuxera's NTFS feature so I could copy >4GB files.
After I formatted the stick I started the copy process back to the stick and little files took forever. I didn't do a bench mark/thoroughput test, but a 1GB file that used to take 2-3 minutes is now sitting at 3 HOURS to complete and even then it will probably increase in time. Oops, yes, now it says 4 HOURS.
it slowly ticks up 21.2 MB, 21.3 MB, 21.4 MB excruciating to say the least.
I expect the 40+GB I had to take at most 40 minutes ~ 1 Hour, not dog slow like it is.
So I thought maybe there was some issue with the format, I plugged it into a Windows 7 PC and formatted it 'normal/not quick' for NTFS - took about an hour to format. By now I'm thinking there is something wrong with the stick.
I then copied a 1GB folder to the stick from Win 7 and it took 2 minutes - reasonable.
Ejected it, plugged it into the MacBook Pro Retina and as you see 3 to 4 hours.
I should say before I started the copy I did like Alexander Hood said with the indexing thing opended preferences and dragged the Patriot drive to Privicy then started the copy.
Sitting at 5 hours now. Gonna cancel it.
I tried both sides of the MacBook just incase perhaps the port was having issues.
I finally got my WD MY Passport and plugged it in (no privacy/index settings with that) and the same file took 3 minutes on the MacBook.
I guess I'll turn in the stick and see if the warranty will cover when a MacBook eats a stick...