I know this has been beaten to death but Apple needs to really step up here.
I had not used my speaker dock in over 2 weeks before upgrading to the iOS6. I use the speaker on my 4S quite regularly and never had ANY audio problems.
It wasn't until after I updated to iOS6 that I realised the sound was gone when I tried to listen to music, videos, etc. I have found that yes, it comes and it goes but there's no controlling it. Sometimes my phone rings, sometimes it doesn't. Sometimes I get an audio notification of emails/texts, etc., sometimes I don't. Someone mentioned they were late for work the other day....I started setting a second alarm just in case.
I've tried docking and undocking or plugging in my headphones, play the first 10 seconds of a track and then unplug the headphones and the volume display disappears immediately. I am VERY careful with my phone and feel this problem was caused solely by upgrading to iOS6.
This is not "just another audio problem".