Hi DJ,
I see no reason to be concerned, other than the things mentioned by Doug. I think they can be resolved in other ways, however. It depends on your setup.
I've been using the Plugable 7-Port Aluminum USB 3.0 hub with the 90.81 firmware upgrade since Sept. and can say I've had zero problems. Micro-B connectors have been occasional problems, but not the hub. This is the first and only hub that has worked for me. The others, including several Anker's, had older chipsets or firmware that could not be updated. I'd be game to try any that had the 90.81 firmware, including Anker; and I will not buy another that uses any older firmware version, or does not state their chipset and firmware versions.
After going through 20 hubs to find one that worked Plugable finally provided an answer to Apple's poor implementation of USB 3.0. Several of these hubs were given to PC users and they love them, but then Windows did USB 3.0 right the first time. [Note, In the interest of full disclosure, that I was provided 2 hubs by Plugable to test. One had the old firmware and is in my closet. The other with the new firmware is on my desk. Since June 2012 I tested 5 hubs for Anker, but they all had the old firmware and presented multiple problems. Supposedly the new ones have overcome this, but I've had no experience with the newer ones. The other hubs, with one exception, were returned for credit.]
I'm using 2.4GHz with my 802.11n Time Capsule and haven't had the problems that Doug had. My hub and Time Capsule are physically separated by several feet. When dealing with radio frequency waves distance is a key factor. If you're having a problem at 2.4 then increase the distance. Since you're using 5MHz you shouldn't have a problem, according to Doug's experience.
With rare exceptions, I plug only USB 3.0 into this hub. I do plug a USB 2.0 hub into the Plugable hub, and all USB 2.0 goes into that hub. Some devices may not work well with USB 3.0 (e.g. Logitech input devices) so the separate hub is wise. Again, I'd keep a several foot separation between the two hubs. This has worked well in my experience. Others have had problems. Plugging the USB 2.0 hub into the USB 3.0 has not posed problems. Best of all, it leaves the Mac's other USB 3.0 port available for charging iOS devices as it can provide the current required, but not provided by USB 3.0 hubs which are only rated for 900ma (0.9 amps). That's short of the 1 or more amps required by iPads, for example.
BTW, lately I've had 7 USB 3.0 portable (x3) and desktop (x4) drives connected to the Plugable (no USB 2.0 at this time.) I've been moving files around and getting organized so it's nice to have all available. No, I don't do huge multiple transfers at the same time so the bandwidth is maintained — for the most part.
That's about all I can think of that may be relevant at this time. Let me know if anything else comes up and what your experience is. Good luck
~
Tim