Topher Kessler wrote:
...but if you want to limit your uses to the Mac App Store, then go ahead and install iAntivirus from the store, which has a couple of decent drawbacks over Sophos and others, primarily because Apple's policies for apps in the store limit their abilies, not only in keeping updated in a timely manner but also in the scope of what they can do for the user.
Since Apple does strictly limit the capabilities of apps downloaded from the Mac App Store, users needing more powerful, full-featured apps are often advised to download them only from "well-known" or "trusted" developers.
That's fine, but in practice it often isn't easy to determine if a developer is very well-known or trustworthy, or even if the download has arrived intact & free of any malicious tampering.
To help with that, Apple developed GateKeeper, a new feature of 10.7.5 & Mountain Lion. That gives users several options, one of which is to allow applications downloaded from both MAS & "identified developers" to open & run. (This is the default setting in Mountain Lion.)
It isn't foolproof -- "identified developers" are basically just those that have obtained an Apple developer ID -- but supporting Gatekeeper is a pretty good indication that the developer is legitimate, & maybe just as importantly that the developer is actively maintaining the app to keep it compatible with the latest versions of OS X. Another benefit is that Gatekeeper detects tampering in developer ID-signed apps.
BTW, in case anyone is wondering, Sophos supports Gatekeeper. The company has also released an updated version of its Mac app specifically for Mountain Lion, so if you decide to install it, make sure you download the right version for the OS you are running.