I think I may have found a fix for this
I have a mid 2009 Macbook Pro, with 4gb ram. After a clean install of Mavericks, I found that memory used was constantly around 3.95Gb of the total 4GB. Even after reboots. I used the sudo /usr/sbin/purge command to free reclaim some ram, the usage was down to 2.6Gb. However, this would only last until the next reboot.
I read somewhere that Mavericks saves the system state during reboots or shutdown, this is excluding the applications. (dont hold me to that)
I tried the following:
1. Close all applications and reboot ("Reopen windows when loggin back in" is not selected)
2. Once you have logged back in, only open Terminal and Type: sudo /usr/sbin/purge (It should prompt for your password)
3. Reboot and again, make sure "Reopen windows when loggin back in" is not selected
You should see that your memory usage has dropped. I also noticed a slight increase in responsiveness.
I am hovering around 2.78Gb when I close down all applications now.
Let me know if this works out for you
Donny