Your System has Run out of Application memory
I upgraded to Mavericks from Mountain Lion, and I have been getting the error message "Your System has Run out of Application memory", and I am forced to restart the computer to be able to keep working.
I have been monitoring the Activity Monitor and I have not found a process that is increasing the amount of memory used. I have seen a proliferation of processes.
I have an iMac 27-inch, Late 2012 with a 3.4 GHz Intel Core i7 and 24 GB 1600 MHz DDR3.
iMac, OS X Mavericks (10.9), 27-inch Late 2012; 3.4 GHz i7; 24GB