Well, I can tell you that the version I have installed is 3.0.1.14012_5 and I'm not able to do any sort of backup off my S4 Active.
In fact, when I turned the phone on while being connected and having Kies running, my Mac crashed something fierce - never seen that before: it dumped console stuff right into the GUI and then rebooted. When it came back up, it forced an fsck that found tons of orphaned files (even though I did a controlled fsck just yesterday).
I'm presuming the crash came from Kies, because that is the first Kernel Extension it listed.
On the Samsung website it lists 10.7 as being the last compatible OS... not sure if their web guy isn't up to speed or if that is the case?
One thing that at least got it to communicate with my S4 was Tools-->Install Driver (it did a driver reinstall - before that it wouldn't even connect).
It's just not Apple Software, is it...