Clancy,
After a brief discussion this afternoon with Motu about another semi-related subject.....
it seems, as Motu have now confirmed..
Please stay tuned to our website, and we will make an announcement when a new driver version is available.
The problem is to be fixed by updated drivers coming from Motu....(and apparently along with some tweaks in Yosemite) that will resolve the issue. (Hopefully)
Time will tell..... but knowing Motu, I expect the update to arrive pretty quickly now the proper cause and therefore method of fix have been identified...
You might also find this update on Motu's website, interesting.... as it also details similar issues with Windows and PC USB3 chipsets.... as well as the specific issue with Motu Midi devices and USB3...
If you are experiencing issues with Windows 7, there may be an issue with your USB chipset. Windows 7, (and previous versions of Windows) is not inherently compatible with USB 3.0. For USB 3.0 connectivity, check with the manufacturer of your USB controller and update the USB chipset drivers for USB 3.0 operation.
To determine which USB ports are USB 3.0, open the Device Manager and look for the "Universal Serial Bus Controllers" category. USB 3.0 devices are commonly (but not always) identified by "USB 3.0", "XHCI", or "SuperSpeed". Check with the manufacturer of your USB 3.0 controller to confirm how their device is labeled in the Device Manager.
Note: Identification can be done by looking at the physical USB port itself; USB 3.0 ports generally have Blue connectors, or are labeled "SS" for SuperSpeed on its exterior.
If you still have issues, consider entering your system's BIOS and disabling USB 3.0 operation to avoid USB 3 compatibility issues with Windows 7. In doing so, your USB 3.0 ports will operate at a USB 2.0 speed, as all versions of USB are backwards compatible. Consult your motherboard or system's manufacturer for instructions on BIOS updates.
Windows 8 natively supports USB 3.0 operation. If you have issues running a MOTU device via USB 3.0 on Windows 8, confirm your USB 3.0 drivers are updated from the manufacturer's Web site. Updating to Windows 8 will alleviate any unresolved Windows 7/USB 3.0 issues.
On Mac OS X, USB 3.0 is supported on Macs running OS X 10.7.5 or later. Be sure you are running OS X 10.7.5, or the latest version of Mountain Lion (OS X 10.8.5) or Mavericks (OS X 10.9.x). If you are experiencing issues with a MOTU MIDI interface connected to Mac OS X via a USB 3.0 connection, test the problematic interface with a powered USB 2.0 hub connected to your computer's on board USB 3.0 port.