I live in NJ and my brother is in lower NY state. My internet connection has been dicey all weekend. (slow load time, pages not loading, timeouts on simple cached pages on my Mac.) This has all been on comcast.
On My brohter's PC using RoadRunner, we have not been able to access the ITMS all weekend.
While iTunes 7 is very buggy, (mac and PC) it seems with so many people having issues specifically from the NE and specifically with Time Warner, Comcast, and Road Runner, I don't think it's an Apple issue.
I am no computing genius and don't know all the ins and outs of how the ISPs and networks work and how the ITMS is only having problems with the northeast. That doesn't make sense with me. I DO know that with almost ALL ISP's, (I've used at least 4 in the last 4 years, 3 in NJ and 1 in FL)) they never accept responsibility for connection issues, they just want you to pay your bills.
It could very well be an Apple problem, but I don't see the symptoms people are reporting to be an Apple issues. It's the same companies (AOL, Time Warner and Road Runner) and the same locals, to be an Apple issue.
(like when my ISP blocks my e-mail server port for my .mac E-Mail account, it's not Apple it's my stupid ISP messing with one of the two recognised e-mail ports.)
Anyway, I don't have any answers, gonna try to do some of what is suggested here (re-authorize, etc) and hope for the best.