Similar problem here:
1. Safari won't open most links, including "open in background". App freezes and won't accept any input (has to be closed via Home).
2. Mail won't open any links
3. Apps using Safari won't open links, and freeze (again having to close app via Home button).
4. Chrome experiencing issues on some webpages, not others (possibly due to different way different links open).
Clearing cache, disabling java, hard reboot all have not resolved.
Apple support advise that it is impossible to downgrade to 9.2.1, which I would have done despite the pain of relaoding music etc.
Online tutorials to downgrade do not work either (as noted by other posters).
This is really really poor from Apple. At the very least they should make the downgrade process easy, to reduce user impact whilst they resolve their all-too-frequent bugs. All those millions of dollars still haven't bought them a robust testing strategy, or a customer-focused mitigation plan.
This is very likely to be the last iPhone I purchase. £550 for this lack of service is appalling. Customer loyalty eroded.