One last follow-up about this ...
In addition to loopback address, should I include the local IP of the server?
At this stage, the results of postfix -n are below.
mail:/etc/postfix root# postconf -n
always_bcc =
command_directory = /usr/sbin
config_directory = /etc/postfix
content_filter = smtp-amavis:[127.0.0.1]:10024
daemon_directory = /usr/libexec/postfix
debug
peerlevel = 2
delay
warningtime = 2h
disable
vrfycommand = yes
enable
serveroptions = yes
inet_interfaces = all
luser_relay =
mail_owner = postfix
mailbox_transport = cyrus
mailq_path = /usr/bin/mailq
manpage_directory = /usr/share/man
maximal
queuelifetime = 1d
message
sizelimit = 0
mydestination = $myhostname,localhost.$mydomain,$mydomain
mydomain = prufrock.com
mydomain_fallback = localhost
myhostname = mail.prufrock.com
mynetworks = 127.0.0.1/32,192.168.0.12/32
mynetworks_style = host
newaliases_path = /usr/bin/newaliases
queue_directory = /private/var/spool/postfix
readme_directory = /usr/share/doc/postfix
relayhost =
sample_directory = /usr/share/doc/postfix/examples
sendmail_path = /usr/sbin/sendmail
setgid_group = postdrop
smtpd
clientrestrictions = permit
saslauthenticated, permit_mynetworks, reject
rblclient zen.spamhaus.org, permit
smtpd
datarestrictions = permit_mynetworks, reject
unauthpipelining, permit
smtpd
enforcetls = no
smtpd
helorequired = yes
smtpd
helorestrictions = permit
saslauthenticated, permit_mynetworks, check
heloaccess hash:/etc/postfix/helo_access, reject
non_fqdnhostname, reject
invalidhostname, permit
smtpd
pw_server_securityoptions = cram-md5,login,plain
smtpd
recipientrestrictions = reject
invalidhostname, reject
non_fqdnsender, reject
non_fqdnrecipient, permit
saslauthenticated, hash:/etc/postfix/rejects, permit_mynetworks, reject
unauthdestination, reject
unlistedrecipient, reject
rblclient zen.spamhaus.org, permit
smtpd
sasl_authenable = yes
smtpd
senderrestrictions = permit
saslauthenticated, permit_mynetworks, reject
non_fqdnsender, permit
smtpd
tlsCAfile = /etc/certificates/mail.prufrock.com.chcrt
smtpd
tls_certfile = /etc/certificates/mail.prufrock.com.crt
smtpd
tls_keyfile = /etc/certificates/mail.prufrock.com.key
smtpd
tlsloglevel = 0
smtpd
use_pwserver = yes
smtpd
usetls = yes
unknown
local_recipient_rejectcode = 550