System performance is slow and Photos app unresponsive

System performance is so bad I can't use the Photos app. Could someone review this EtreCheck report and help me understand what I can do to fix performance problems on my iMac?

I went to Photos while in safe boot and the system froze.

Note that I am not using iCloud.

EtreCheck version: 3.4.6 (460)

Report generated 2017-10-15 13:58:50

Download EtreCheck from https://etrecheck.com

Runtime: 2:29

Performance: Excellent

Click the [Lookup] links for more information from Apple Support Communities.

Click the [Details] links for more information about that line.

Problem: Computer is too slow

Description:

Photos app is especially slow and unresponsive

Hardware Information: ⓘ

iMac (21.5-inch, Mid 2011)

[Technical Specifications] - [User Guide] - [Warranty & Service]

iMac - model: iMac12,1

1 2.5 GHz Intel Core i5 (i5-2400S) CPU: 4-core

20 GB RAM Upgradeable - [Instructions]

BANK 0/DIMM0

2 GB DDR3 1333 MHz ok

BANK 1/DIMM0

2 GB DDR3 1333 MHz ok

BANK 0/DIMM1

8 GB DDR3 1333 MHz ok

BANK 1/DIMM1

8 GB DDR3 1333 MHz ok

Handoff/Airdrop2: not supported

Wireless: en1: 802.11 a/b/g/n

Video Information: ⓘ

AMD Radeon HD 6750M - VRAM: 512 MB

iMac 1920 x 1080

Disk Information: ⓘ

WDC WD5000AAKS-402AA0 disk0: (500.11 GB) (Rotational)

[Show SMART report]

EFI (disk0s1 - MS-DOS FAT32) <not mounted> [EFI]: 210 MB

Macintosh HD (disk0s2 - Journaled HFS+) / [Startup]: 499.25 GB (304.79 GB free)

Recovery HD (disk0s3 - Journaled HFS+) <not mounted> [Recovery]: 650 MB

HL-DT-STDVDRW GA32N ()

USB Information: ⓘ

USB20Bus

Apple Inc. FaceTime HD Camera (Built-in)

hub_device

HP External HDD

External HDD disk1: (319.37 GB)

EFI (disk1s1 - MS-DOS FAT32) <not mounted> [EFI]: 210 MB

HP SimpleSave (disk1s2 - Case-sensitive Journaled HFS+) /Volumes/HP SimpleSave : 319.03 GB (1.43 GB free)

Virtual CD 4507 disk2: (804.4 MB)

(disk2s0) <not mounted> [partition_scheme]: 700 MB

(disk2s0s1) <not mounted> [partition_map]: 1 KB

HP Launcher (disk2s0s2 - HFS) /Volumes/HP Launcher : 903 KB (23 KB free)

Apple Inc. BRCM2046 Hub

Apple Inc. Bluetooth USB Host Controller

USB20Bus

hub_device

Apple Computer, Inc. IR Receiver

Apple Internal Memory Card Reader

Thunderbolt Information: ⓘ

Apple Inc. thunderbolt_bus

System Software: ⓘ

macOS High Sierra 10.13 (17A405) - Time since boot: less than an hour

Gatekeeper: ⓘ

Mac App Store and identified developers

Kernel Extensions: ⓘ

/System/Library/Extensions

[not loaded] com.devguru.driver.SamsungComposite (1.4.42 - SDK 10.6) [Lookup]

/System/Library/Extensions/ssuddrv.kext/Contents/PlugIns

[not loaded] com.devguru.driver.SamsungACMControl (1.4.42 - SDK 10.6) [Lookup]

[not loaded] com.devguru.driver.SamsungACMData (1.4.42 - SDK 10.6) [Lookup]

[not loaded] com.devguru.driver.SamsungMTP (1.4.42 - SDK 10.5) [Lookup]

[not loaded] com.devguru.driver.SamsungSerial (1.4.42 - SDK 10.6) [Lookup]

System Launch Agents: ⓘ

[not loaded] 9 Apple tasks

[loaded] 180 Apple tasks

[running] 99 Apple tasks

System Launch Daemons: ⓘ

[not loaded] 36 Apple tasks

[loaded] 188 Apple tasks

[running] 106 Apple tasks

Launch Agents: ⓘ

[not loaded] com.oracle.java.Java-Updater.plist (? 0 ? - installed (null)) [Lookup]

Launch Daemons: ⓘ

[loaded] com.adobe.fpsaud.plist (? 2afb3af7 ebe01993 - installed 2017-09-26) [Lookup]

[not loaded] com.apple.installer.cleanupinstaller.plist (? 1963bf56 0 - installed 2017-09-28)

[not loaded] com.oracle.java.Helper-Tool.plist (? 0 ? - installed (null)) [Lookup]

User Launch Agents: ⓘ

[loaded] com.google.keystone.agent.plist (Google, Inc. - installed 2017-09-27) [Lookup]

[running] com.spotify.webhelper.plist (Spotify - installed 2017-10-15) [Lookup]

User Login Items: ⓘ

Spotifree Application - Hidden

(/Applications/Spotifree.app)

fuspredownloader Application

(~/Library/Application Support/.FUS/fuspredownloader.app)

Internet Plug-ins: ⓘ

FlashPlayer-10.6: 27.0.0.159 (installed 2017-10-10) [Lookup]

QuickTime Plugin: 7.7.3 (installed 2017-09-21)

Flash Player: 27.0.0.159 (installed 2017-10-10) [Lookup]

User internet Plug-ins: ⓘ

ContentManager: Unknown

RocketEngine: Unknown

UploadManager: Unknown

Safari Extensions: ⓘ

[enabled] Adblock Plus - Eyeo GmbH - https://adblockplus.org/ (installed 2016-12-21)

[enabled] AdBlock - BetaFish, Inc. - https://getadblock.com (installed 2017-08-09)

[enabled] WOT - WOT Services Ltd - http://www.mywot.com/ (installed 2016-04-22)

3rd Party Preference Panes: ⓘ

Flash Player (installed 2017-09-26) [Lookup]

Time Machine: ⓘ

Skip System Files: NO

Mobile backups: OFF

Auto backup: YES

Volumes being backed up:

Macintosh HD: Disk size: 499.25 GB Disk used: 194.46 GB

Destinations:

HP SimpleSave [Local]

Total size: 319.03 GB

Total number of backups: 97

Oldest backup: 2016-10-16, 10:22 AM

Last backup: 2017-10-15, 1:15 PM

Size of backup disk: Too small

Backup size 319.03 GB < (Disk used 194.46 GB X 3)

Top Processes by CPU: ⓘ

2% WindowServer

1% kernel_task

0% fontd

0% sysmond

0% com.apple.accessibility.mediaaccessibilityd

Top Processes by Memory: ⓘ

983 MB kernel_task

775 MB Safari

180 MB mds_stores

169 MB Numbers

133 MB photoanalysisd

Top Processes by Network Use: ⓘ

Input Output Process name

56 KB 51 KB mDNSResponder

5 KB 5 KB apsd

522 B 354 B netbiosd

0 B 64 B SystemUIServer

Top Processes by Energy Use: ⓘ

5.14 WindowServer

0.66 sysmond

0.08 Activity Monitor

0.04 cfprefsd

Virtual Memory Information: ⓘ

15.55 GB Available RAM

11.91 GB Free RAM

4.45 GB Used RAM

3.64 GB Cached files

0 B Swap Used

Software installs (last 30 days): ⓘ

Evernote: 6.12.2 (installed 2017-09-21)

Notebook: 3.0 (installed 2017-09-21)

Todoist: 7.0.3 (installed 2017-10-02)

Evernote: 6.12.3 (installed 2017-10-02)

PhotoSweeper: 3.1.0 (installed 2017-10-02)

Adobe Flash Player: (installed 2017-10-10)

Install information may not be complete.

Diagnostics Events (last 3 days for minor events): ⓘ

2017-10-15 13:40:03 Last shutdown cause: 3 - Hard shutdown

2017-10-15 13:33:17 Photos.app High CPU use [Open] [Details]

2017-10-15 12:59:46 com.apple.WebKit.WebContent High CPU use [Open] [Details]

2017-10-14 12:09:28 Dock.app Crash [Open]

Cause: /Library/Widgets/Web Clip.wdgt

/Library/Widgets/Calculator.wdgt

/Library/Widgets/Weather.wdgt

/Library/Widgets/Unit Converter.wdgt

/Users/cathy/Library/Widgets/Epicurious.wdgt

/Library/Widgets/Stickies.wdgt

/Library/Widgets/Stickies.wdgt

/Library/Widgets/World Clock.wdgt

/Library/Widgets/Stickies.wdgt

2017-10-13 14:52:33 mds_stores Crash [Open]

Cause: [0x7000102ad000] Caught mach exception

[0x7000102ad000] ContentIndexQuery.c:1156: failed assertion '0' /.Spotlight-V100/Store-V2/8B19522B-6EB0-4C36-AF11-4999B8AE733A (hfs, t: 0x17, st: 0x1, f: 0x480d000) Expected valid doc set type. Got -1890545200 7fd7 -1890546480 -1890546256 32727 -1890545904 negated

[0x7000102ad000] Caught mach exception

[0x7000102ad000] ContentIndexQuery.c:1156: failed assertion '0' /.Spotlight-V100/Store-V2/8B19522B-6EB0-4C36-AF11-4999B8AE733A (hfs, t: 0x17, st: 0x1, f: 0x480d000) Expected valid doc set type. Got -1890545200 7fd7 -1890546480 -1890546256 32727 -1890545904 negated

[0x7000102ad000] Caught mach exception

[0x7000102ad000] ContentIndexQuery.c:1156: failed assertion '0' /.Spotlight-V100/Store-V2/8B19522B-6EB0-4C36-AF11-4999B8AE733A (hfs, t: 0x17, st: 0x1, f: 0x480d000) Expected valid doc set type. Got -1970161856 7fd7 -1970143312 -1970142960 32727 -1970142608 negated

[0x7000102ad000] Caught mach exception

[0x7000102ad000] ContentIndexQuery.c:1156: failed assertion '0' /.Spotlight-V100/Store-V2/8B19522B-6EB0-4C36-AF11-4999B8AE733A (hfs, t: 0x17, st: 0x1, f: 0x480d000) Expected valid doc set type. Got -1970161856 7fd7 -1970143312 -1970142960 32727 -1970142608 negated

Initializing