I have typically have just upgraded my Macs with each new OS, and I have not experienced a lot or mail problems before this one. The only other issue I have had is with unreliable search results, not finding emails that I know are there and a search should have located. This issue has been ongoing for several years.
However, because of some other wanky issues I was having, I think due to trying to run Windows with Parallels, I decided to do a clean OS install with High Sierra, and migrate my data over manually. Everything was fine initially, but this problem started showing up after I did the 10.13.3 incremental upgrades in early February.
I have to agree with several other posters that this is a major issue and one that Apple should fix sooner rather than later.