Thanks for that. I tried everything and problem still persists. Here is my report from the Etrecheck...
EtreCheck version: 3.4.6 (460)
Report generated 2017-11-23 16:38:28
Download EtreCheck from https://etrecheck.com
Runtime: 4:04
Performance: Good
Click the [Lookup] links for more information from Apple Support Communities.
Click the [Details] links for more information about that line.
Click the [Remove/Report] links to remove adware or update the whitelist of legitimate software.
Click the [Clean up] link to delete unused files.
Problem: Computer is too slow
Hardware Information: ⓘ
iMac (21.5-inch, Late 2013)
[Technical Specifications] - [User Guide] - [Warranty & Service]
iMac - model: iMac14,3
1 2.9 GHz Intel Core i5 (i5-4570S) CPU: 4-core
8 GB RAM Upgradeable - [Instructions]
BANK 0/DIMM0
4 GB DDR3 1600 MHz ok
BANK 1/DIMM0
4 GB DDR3 1600 MHz ok
Handoff/Airdrop2: supported
Wireless: en1: 802.11 a/b/g/n/ac
iCloud Quota: 578 MB available
Video Information: ⓘ
NVIDIA GeForce GT 750M - VRAM: 1 GB
iMac 1920 x 1080
Disk Information: ⓘ
APPLE HDD HTS541010A9E662 disk0: (1 TB) (Rotational)
[Show SMART report]
EFI (disk0s1 - MS-DOS FAT32) <not mounted> [EFI]: 210 MB
(disk0s2) <not mounted> [CoreStorage Container]: 999.35 GB
Recovery HD (disk0s3 - Journaled HFS+) <not mounted> [Recovery]: 650 MB
USB Information: ⓘ
USB30Bus
Apple Inc. BRCM20702 Hub
Apple Inc. Bluetooth USB Host Controller
Apple Inc. FaceTime HD Camera (Built-in)
Thunderbolt Information: ⓘ
Apple Inc. thunderbolt_bus
Virtual disks: ⓘ
Macintosh HD (disk1 - Journaled HFS+) / [Startup]: 999.01 GB (638.85 GB free)
Physical disk: disk0s2 999.35 GB Online
System Software: ⓘ
macOS High Sierra 10.13.1 (17B48) - Time since boot: about 4 days
Gatekeeper: ⓘ
Mac App Store and identified developers
Possible adware: ⓘ
Adware: ~/Library/LaunchAgents/com.spigot.ApplicationManager.plist
One possible adware file found. [Remove/Report]
Clean up: ⓘ
/Library/LaunchAgents/com.nike.nikeplusconnect.plist
/Applications/Nike+ Connect.app/Contents/MacOS/Nike+ Connect Helper Daemon
Executable not found!
~/Library/LaunchAgents/com.bittorrent.BitTorrent.plist
/usr/bin/open -n /Applications/BitTorrent.app
Executable not found!
2 orphan files found. [Clean up]
Kernel Extensions: ⓘ
/System/Library/Extensions
[not loaded] com.nike.sportwatch (1.0.0) [Lookup]
/Users/[redacted]/Apowersoft/Mac Online Launcher/Mac Online Launcher.app
[loaded] com.Apowersoft.driver.AudioDevice (1.6.7 - SDK 10.11) [Lookup]
[not loaded] com.Cycling74.driver.Soundflower (1.0.0 - SDK 10.8) [Lookup]
System Launch Agents: ⓘ
[not loaded] 8 Apple tasks
[loaded] 167 Apple tasks
[running] 113 Apple tasks
System Launch Daemons: ⓘ
[failed] com.apple.loginwindow.plist (Apple, Inc. - installed 2017-11-02)
[not loaded] 37 Apple tasks
[loaded] 174 Apple tasks
[running] 118 Apple tasks
Launch Agents: ⓘ
[failed] com.adobe.ARMDCHelper.cc24aef4a1b90ed56a725c38014c95072f92651fb65e1bf9c8e43c37a2 3d420d.plist (Adobe Systems, Inc. - installed 2017-01-11) [Lookup]
[failed] com.nike.nikeplusconnect.plist (? c057c0cc 0 - installed 2015-10-09) [Lookup] - /Applications/Nike+ Connect.app/Contents/MacOS/Nike+ Connect Helper Daemon: Executable not found!
[loaded] org.macosforge.xquartz.startx.plist (Apple Inc. - XQuartz - installed 2016-10-26) [Lookup]
Launch Daemons: ⓘ
[loaded] com.adobe.ARMDC.Communicator.plist (Adobe Systems, Inc. - installed 2017-01-11) [Lookup]
[loaded] com.adobe.ARMDC.SMJobBlessHelper.plist (Adobe Systems, Inc. - installed 2017-01-11) [Lookup]
[loaded] com.adobe.fpsaud.plist (? 2afb3af7 a56d5fc2 - installed 2017-10-26) [Lookup]
[not loaded] com.apple.installer.cleanupinstaller.plist (? 1963bf56 0 - installed 2017-09-27)
[loaded] com.macpaw.CleanMyMac3.Agent.plist (MacPaw Inc. - installed 2016-11-15) [Lookup]
[loaded] com.microsoft.autoupdate.helper.plist (Microsoft Corporation - installed 2017-10-15) [Lookup]
[loaded] com.microsoft.office.licensingV2.helper.plist (Microsoft Corporation - installed 2015-09-11) [Lookup]
[loaded] org.macosforge.xquartz.privileged_startx.plist (Apple Inc. - XQuartz - installed 2016-10-26) [Lookup]
User Launch Agents: ⓘ
[loaded] com.bittorrent.BitTorrent.plist (? 628d211c 0 - installed 2016-01-07) [Lookup] - /Applications/BitTorrent.app: Executable not found!
[loaded] com.cisco.videoguard7.plist (Shell Script c8b7826e - installed 2017-09-21)
[loaded] com.cisco.videoguard7.uninstall.plist (Shell Script 52519eca - installed 2017-09-21)
[running] com.cisco.videoguardmonitor.plist (Shell Script 2864b4de - installed 2017-09-21)
[loaded] com.google.keystone.agent.plist (Google, Inc. - installed 2017-09-28) [Lookup]
[loaded] com.macpaw.CleanMyMac3.Scheduler.plist (MacPaw Inc. - installed 2016-11-15) [Lookup]
[running] com.spigot.ApplicationManager.plist (? d296c714 217327b7 - installed 2016-12-29) Adware! [Remove/Report]
~/Library/Application Support/Spigot/ApplicationManager
[loaded] com.spotify.webhelper.plist (Spotify - installed 2017-01-27) [Lookup]
Internet Plug-ins: ⓘ
FlashPlayer-10.6: 27.0.0.187 (installed 2017-11-15) [Lookup]
QuickTime Plugin: 7.7.3 (installed 2017-09-21)
AdobePDFViewerNPAPI: 17.012.20098 (installed 2017-11-14) [Lookup]
AdobePDFViewer: 18.009.20044 (installed 2017-11-14) [Lookup]
Flash Player: 27.0.0.187 (installed 2017-11-15) [Lookup]
PepperFlashPlayer: 27.0.0.187 (installed 2017-11-15) [Lookup]
Silverlight: 5.1.50901.0 (installed 2016-12-20) [Lookup]
Safari Extensions: ⓘ
[disabled] AdBlock - BetaFish, Inc. - https://getadblock.com (installed 2017-11-23)
3rd Party Preference Panes: ⓘ
Flash Player (installed 2017-10-26) [Lookup]
Time Machine: ⓘ
Time Machine not configured!
Top Processes by CPU: ⓘ
8% mds
7% kernel_task
6% mdworker
6% mdworker
5% mdworker
Top Processes by Memory: ⓘ
930 MB kernel_task
583 MB Safari
449 MB com.apple.WebKit.WebContent
306 MB com.apple.WebKit.WebContent
178 MB Mail
Top Processes by Network Use: ⓘ
Input Output Process name
8 MB 1 MB mDNSResponder
8 MB 121 KB com.apple.WebKit.Networking
234 KB 11 KB Mail
17 KB 27 KB ath
22 KB 15 KB netbiosd
Top Processes by Energy Use: ⓘ
10.76 com.apple.WebKit.WebContent
9.60 WindowServer
3.88 Safari
0.80 hidd
Virtual Memory Information: ⓘ
1.55 GB Available RAM
34 MB Free RAM
6.45 GB Used RAM
1.52 GB Cached files
148 MB Swap Used
Software installs (last 30 days): ⓘ
Adobe Flash Player: (installed 2017-10-25)
Adobe Pepper Flash Player: (installed 2017-10-25)
Adobe Acrobat Reader DC (18.009.20044): (installed 2017-11-14)
Adobe Flash Player: (installed 2017-11-15)
Microsoft Word for Mac: (installed 2017-11-15)
Adobe Pepper Flash Player: (installed 2017-11-15)
Microsoft Excel for Mac: (installed 2017-11-19)
Install information may not be complete.