John,
You will get the same performance from your Hard Disk Drive whether you use USB 3 or Thunderbolt 3.
The choke point in all hard drive setups is the hard drive controller, the interface between the SATA connector and the storage platters in your HDD. USB/Thunderbolt cable speeds don't matter when your HDDs are only capable of read/write speeds at around 100MBps each. In other words, there is no significant difference between plugging your external USB HDD drive in your USB port versus going through the adapter to Thunderbolt.
Yes, you can get a NAS, more Hard Disk Drives, and set your 7200rpm drives to mirror in Raid 1 or Raid 10. This will double your read speed, but your write speed won't improve. The only real difference for you is that Thunderbolt will attempt to auto-recover when re-connected after an accidental disconnect. USB won't. Thunderbolt will also daisy chain from device to device where USB must split through powered Hubs.
If you really want to see a difference, take the big step into Solid State Drives. The basic SSDs of today have throughputs of 400MBps-500MBps. Yes, they cost more per gigabyte, but with a good NAS, you can replicate one large HDD with several small affordable SSDs in Raid 5/6. This costs a little more, but it is faster and more reliable.
There is one catch:
If the internal drive in your computer is an HDD, you won't feel the full difference between an external HDD and an external SSD. Your internal HDD isn't able to receive data as fast as an SSD can send it. If you really want to feel the difference, replace your internal HDD with an SSD. The first time you run your operating system on an SSD, you won't go back.
You can also take your USB 3 HDD to a computer operating on an internal SSD. Try transferring files between your external USB HDD and the internal SSD. Then try transferring between an external SSD and an internal SSD. It won't matter if the external SSD is USB or Thunderbolt. You will instantly see the difference.