Vanishing printers

You might try resetting the printer system: If you can't print from your Mac or iOS device - Apple Support (see the paragraph about 3/4 down the page).

Also how are the printers connected to your Mac? If it's by cable try resetting the SMC: How to reset the System Management Controller (SMC) on your Mac - Apple Support

The next time the printers go away try just relaunching the Finder and see if that will bring them back.

Also, log into another user account on your Mac and run for a while to see if the problem persists there.

If it doesn't log back into your account, download and run Etrecheck. Copy and paste the results into your reply. Etrecheck is a diagnostic tool that was developed by one of the most respected users here in the ASC and recommended by Apple Support to provide a snapshot of the system and help identify the more obvious culprits that can adversely affect a Mac's performance.

I have had the same issue for over a year now. It doesn’t matter which os I’ve been using at the time either. Each time I shut down or restart my Mac, it loses all printers.

I’m a graphic artist and have 5 printers to set up each day before I can begin work. It’s become a very frustrating daily routine for me. Reset printing system, add each printer, set up each printers settings.... surely someone has a fix? I’ve done absolutely everything suggested by apple plus more and nothing works. Not even a short term fix.