I've done a little bit of searching on google and had no idea that this problem has been happening for YEARS... The ONLY solution I saw was for this Sony Driver, which i'm sure everyone here already seen... I haven't had any problem burning until iTunes 8.0...
Anyway, I tried that (Sony Drive), even tried the RegCure (whatever) but it wasn't exactly "Free", so that was a dead end... I even tried lower burning speeds...still nothing... As you know, I have two discs left to burn for a friend...
I just gave up on iTunes and burned it with my Windows Media Player... Just lucky for me, I burn all my purchases from iTunes to an Audio CD in case something happens to my CPU (also so I can import to my Xbox 360)... And once I do that, I re-import them so I can listen to the albums on my WMP...
But as I was saying, I just used my WMP to burn the album that wouldn't burn in iTunes... After everything burned fine, I went back to iTunes for the other disc and suprise, suprise...it burned without any problem... WTH, right?¿?
It may have something to do with the discs i'm using... Because I inserted a Maxell Pro discs to "test" the burn out in iTunes... It burned without a hitch (before I used the above method) but because of this, I only let it burn for 5 seconds; because it usually cancels out in 3 from the error... I was only trying to test the burn, and was surprised that it started burning... It was a better quality discs and I didn't want to burn the album that I was testing on it... I tried to cancel but 5 seconds was too long...ruined the disc..
lol
So for clarity the disc i'm getting the error with is a Memorex disc... And its possible that they are to cheap...which was pointed out during my research online... But the problem with that theory is, I already burned 12 discs using those Memorex discs; so why NOW do I constantly get the error?¿? I couldn't be, totally the fault of disc quality...but then again who knows...
All I know is, as of now...I was able to burn another CD on iTunes after burning 1 from WMP first... Since I don't have anything else to burn (or that I want to) at the moment; as far as I know, i'm just waiting to get the error again... Which from my history could be 4-6 more disc down the line...
Another possibility could be that I actually burned the CD when I had WMP open... Maybe iTunes burning needs a "crutch" to be free from the error and after you burn one; you can burn a few CD's without worry of the error...
Sorry to be throwing so many "theories" out there, but having something to work on, is better than nothing... Once I have other CD's to burn, i'll come back with an update and tell you how many burns I got with iTunes before I got the error again...
Disclaimer:
This is just my experience... I realize that many people have tried all sorts of CD-R discs and different burning software/hardware/whatever and they still get an 4280 error... I'm not trying to create false hope, as i've seen being pointed out from frustrated users...
So to summarize, individual results may vary... :P