Error 0xE8000065
Dell Latitude D510, Windows XP
Dell Latitude D510, Windows XP
This has been happening to me for a few weeks. Same error. Today after it happened again, I unplugged my lightning cable from one USB port in my computer and put it in a different port.
iTunes opened just fine and went through the backup process flawlessly.
Can't say why this fixed it, but it did.
Error 0xE8000065