You think its better to put those additional folders somewhere else? Could that be confusing the finder?
No, it doesn't confuse the Finder, but it is not the place to store user data. If you need a shared folder, put it in /Users/Shared/. If it isn't shared, put it in your home under Documents or somewhere else.
If it needs to be private, then you need to either create the folder in one of the protected subfolders of your Home (Documents, Desktop, Pictures, Music, Downloads), or change the permissions on the newly created folder to remove the group (Staff) and set everyone to "no access."
A virus or malware didn't cause the problem with the folder. It does happen rarely as I have seen reports of it here on ASC. I have not seen a solution, though.
You should always have a backup, and if you are using flash media as a permanent storage medium, you are choosing poorly. They are not reliable enough for that purpose.