Trend Micro acknowledges a problem with 10.15.1. Below is what they advised me to do.
This is Allen from Trend Micro Consumer Support.
I understand that you encountered issues after upgrading the Mac OS of your computer and also your Trend Micro security. We apologize for the inconvenience this has caused you.
This happens because there are some enhancements done by Apple on macOS 10.15.1 and these enhancements are conflicting with the latest version of Trend Micro.
However, we recently released a hotfix for the issue. Kindly refer to the link below about the hotfix for the issue that you have encountered:
https://esupport.trendmicro.com/en-us/home/pages/technical-support/antivirus-for-mac/1123982.aspx