Personally I wouldn't use "combo cleaner" .
1. Remove adware if installed on your Mac..
Run the latest release of Malwarebytes for Mac to remove malware/adware, if installed on your Mac.
For instructions: Install Malwarebytes for Mac v4 Uninstall Malwarebytes for Mac
Click the “FREE DOWNLOAD” button.
Click the “Scan ” button. Once done, quit Malwarebytes for Mac.
Restart the computer and relaunch Safari holding the shift key down.
Scan for Malware again.
Additional steps if necessary.
2. Reset search engine: https://support.apple.com/guide/safari/customize-your-search-ibrwe75c2a3c/mac
3. Reset Homepage. https://support.apple.com/guide/safari/set-your-homepage-ibrw1020/mac
4. Remove unknown extensions: Safari > Preferences > Extensions
https://support.apple.com/guide/safari/use-safari-extensions-sfri32508/mac
Reboot the Mac
Malware Removal Tool
Should malware make its way onto a Mac, macOS also includes technology to remediate infections. The Malware Removal Tool (MRT) is an engine in macOS that remediates infections based on updates automatically delivered from Apple (as part of automatic updates of system data files and security updates). MRT removes malware upon receiving updated information, and it continues to check for infections on restart and login. MRT doesn’t automatically reboot the Mac.
https://support.apple.com/guide/security/protecting-against-malware-sec469d47bd8/web