Audio interface usb-c connection

Hi there, Idkanything69! Thanks for reaching out to Apple Support Communities. 

After reviewing your post, it sounds like you are running into some issues with your audio interface suddenly not working with your Mac as expected. We definitely understand that can be a concern and we'd love to help. Let’s start our investigation by determining exactly when this happens. First, test for this behavior in safe mode: Start up your Mac in safe mode.

Next, see if this behavior persists in a second user account on your Mac. If you don't have one you can use, please follow these steps to make a test account that can be deleted later: Set up users, guests, and groups on Mac.

Please let us know if you have follow-up questions about this issue, or if the issue remains unresolved. Have a great day!

Thanks for getting back with us about this, Idkanything69. Since it happens in all modes on your Mac, we'd like to look into possible hardware interaction issues. Do you happen to have another audio interface you can test with your Mac? Testing with a different computer would be helpful too, so we can see if the behavior persists.

You might also check that the device firmware is updated, if there are updates provided by the manufacturer.

Please let us know how that all goes and we'll continue working with you to narrow down the issue. Take care.