Multiple serious problems with the two laptops I use for my medical practice.

Do you have a backup strategy in place, i.e. either Time Machine or an external clone of the laptops hard drive?

CleanMyMac is considered by most of the experienced contributors to these forums to be akin to malware. It should be removed according to the developer's instructions. To check to see if you've removed all of the supporting files by downloading and running the shareware app Find Any File to search for any files with the application's or the developer's name in the file name.  For the CMM software you'd do the following search(es): 

1 - Name contains cleanmymac

2 - Name contains macpaw

Any files that are found can be dragged from the search results window to the Desktop or Trash bin in the Dock for deletion.

FAF can search areas that Spotlight can't like invisible folders, system folders and packages.  

There is no reason to ever install or run any 3rd party "cleaning", "optimizing", "speed-up", anti-virus, VPN or security apps on your Mac.  This user tip describes what you need to know and do in order to protect your Mac: Effective defenses against malware and other threats - Apple Community.  

There are no known viruses, i.e. self propagating, for Macs.  There are, however, adware and malware which require the user to install although unwittingly most of the time thru sneaky links, etc.   

Anti Virus developers try to group all types as viruses into their ad campaigns of fear.  They do a poor job of the detecting and isolating the adware and malware.  Since there are no viruses these apps use up a lot of system resources searching for what is non-existent and adversely affect system and app performance.

There is one app, Malwarebytes, which was developed by a long time contributor to these forums and a highly respected member of the computer security community, that is desshoigned solely to seek out adware and known malware and remove it.  The free version is more than adequate for most users.  

Also, unless you're using a true VPN tunnel, such as between you and your employer's or bank's servers, they are useless from a privacy standpoint: Public VPN's are anything but private.  

To give us a sanitized look at your laptop's setup, both hardware and software wise, download and run Etrecheck. Etrecheck is a diagnostic tool that was developed by one of the most respected users here in the ASC and recommended by Apple Support  to provide a snapshot of the system and help identify the more obvious culprits that can adversely affect a Mac's performance.

IMPORTANT:

Before running Etrecheck assign Full Disk Access to Etrecheck in the Etrecheck's Privacy preference pane so that it can get additional information from the Console and log files for the report:

Also click and read the About info to further permit full disk access.

Copy the report

and use the Additional Text button to include the report in your reply.

Then we can examine the report and see if we can determine what might be causing the problem.

You need to hire an IT Consultant to get your practice securely and correctly set up. Why would you jeopardize your practice and patient data performing your own IT configuration and setup? It is obvious that you are not as familiar with IT as you believe you are; you are using CleanMyMac, and have not created a sufficient backup mechanism/policy.

If you are using an online service to store patient data you better make sure they are HIPAA compliant. And, you can't depend on online storage for backup.

Ask other physicians, clinics, or associations in your area for IT Consultant recommendations.

Can you click on the Additional Text button to bright up the new window? If you can then open the report, select all and copy and paste into the Additional text window. It has to be done thru the browser.

You really need to get a consultant. Why are you as a physician spending all this time on troubleshooting your practice computer? You need it professionally configured to protect your patients' data from loss or compromise. How many of your patients self diagnose and write their own prescriptions? When they need specialized assistance they consult with you. You need specialized assistance. It is clear you are not familiar with HIPAA, security, and other required computer systems used in a medical practice.

I am not saying this out of disrespect but only because I think you can best be served by hiring a professional.

The additional text button will show up in the topic when you are replying to a post. It's in the tool bar at the botton of the Reply window: