Several problems that I can see from the report. I will list some of them below.
Your mac has a rotating hard drive. HD are much slower than SSD, and with newer OS versions that difference is ever more noticeable. You also apparently have an external SSD. That may give you a good solution going forward, I will write about it in another post.
You have several kernel extensions, some quite old:
Kernel Extensions:
/Library/Extensions
[Not Loaded] FTDIKext.kext - com.FTDI.driver.D2XXHelper (1.0 - SDK 10.14)
[Not Loaded] FTDIUSBSerialDriver.kext - com.FTDI.driver.FTDIUSBSerialDriver (2.3 - SDK 10.9)
[Not Loaded] hp_fax_io.kext - com.hp.kext.hp-fax-io (5.11.0 - SDK 10.8)
[Not Loaded] hp_io_enabler_compound.kext - com.hp.kext.io.enabler.compound (3.2.0)
[Not Loaded] hp_Inkjet9_io_enabler.kext - com.hp.print.hpio.Inkjet9.kext (2.3.1 - SDK 10.8)
[Not Loaded] MotMobileUSB.kext - com.motorola-mobility.driver.MotMobileUSB (1.2.2 - SDK 10.5)
[Not Loaded] kudshawking.kext - hk.uds.netusb.controller (1.59)
Note that one that says SDK 10.5? 10.8?
Do you still need a driver for a Motorola device from ten years ago?
Under Launch Agents, you also have a few:
Launch Agents:
[Not Loaded] com.adobe.AAM.Updater-1.0.plist (? ffb65062 - installed 2018-07-14)
[Other] com.adobe.ARMDCHelper.cc24aef4a1b90ed56a725c38014c95072f92651fb65e1bf9c8e43c37a23d420d.plist (Adobe Systems, Inc. - installed 2021-02-10)
[Not Loaded] com.adobe.AdobeCreativeCloud.plist (Adobe Systems, Inc. - installed 2018-07-14)
[Loaded] com.adobe.ElementsAutoCreator-17.0.plist (Adobe Systems, Inc. - installed 2018-11-17)
[Running] com.adobe.GC.AGM.plist (Adobe Systems, Inc. - installed 2021-04-16)
[Not Loaded] com.adobe.GC.Invoker-1.0.plist (Adobe Systems, Inc. - installed 2021-04-16)
[Other] com.brother.LOGINserver.plist (? a1772de2 - installed 2015-03-12)
[Loaded] com.google.keystone.agent.plist (Google, Inc. - installed 2021-03-04)
[Loaded] com.google.keystone.xpcservice.plist (Google, Inc. - installed 2021-03-04)
[Other] com.mcafee.McAfeeSafariHost.plist (? 0 - installed 2018-10-22)
Notably, you have still remnants of mcafee. The google keystone stuff are known hog resources.
I am not familiar with this "pcshow" software, but it installs several agents and daemons. It may be just fine, I am just not familiar with it.