Hi
I had this exact problem and did the following:
- Firstly I connected the printer to my wifi and made sure my imac was on the same network
- I then setup the printer over wifi on my imac (it used AirPrint)
- Then navigate to Finder -> Go( in the menu at the top) -> Macintosh HD -> Library -> Image Capture -> Devices
- Copy "Epson Scanner" to your Desktop and alter the permissions for everyone and staff to "Read & Write", to alter permissions right click on "Epson Scanner" and go to get info and permissions are at the bottom
- Delete the Original "Epson Scanner" Plugin from Devices Folder
- Copy the "Epson Scanner" from the desktop with custom permission to Devices Folder
- Try opening the scanner now, may need a restart
If you want to go back to a wired connection to the printer like I did then just setup the printer with a wired connection you do not need to do all the above again, you can even go back to Finder -> Go -> Macintosh HD -> Library -> Image Capture -> Devices and change the "Epson Scanner" everyone permission back to read only.
By the way this assumes you have all of the relevant drivers installed.
Hopefully this helps