I don't see any of the usual suspects in your report. However, you did or do have VirusBarrier Scanner installed. You should uninstall it according to the developer's instructions. You do not need any "cleaning", "optimizing", "speed-up", anti-virus or VPN apps on your Mac, ever!
Also you haven't booted for 7 days. You should reboot more frequently, like every other day. That will clean out temporary system and applications cache and swap files and help keep the system and applications more efficiently. I shut down at night and boot up in the morning. The time it takes is not an inconvenience.
You have quite a few apps in your System/Users & Groups/Login Items preference pane and running in the background. Remove all of them from the preference pane and open them only when needed and close when done. They can be added to the Dock for easy access.
You have a Fusion drive. Boot into the Recovery volume (boot with the Command + R keys held down), launch Disk Utility and run First aid on all volumes. If you get any errors reported make a note them and rerun First Aid till there are no errors reported.