Leave them alone unless one what a bigger disaster.
The first 600 posting all point to the same thing, Remove " CleanMyMac "
As Testament read a few https://discussions.apple.com/search?q=cleanmymac and then Remove as per the Developers Instructions.
Please, do not install an Uninstaller to perform this action as they too tend to destroy the OS.
Any Third Party Applications that will interfere with the normal operation of the OS, alter, modify, remove or delete or attempt to do so is an invitation for disaster and may require a Reinstallation of the OS.
This includes AntiVirus, Disk Cleaners, Disk Optimizes, UnInstaller etc.
And CleanMyMac is in this category
The The Built in Security is all that is required.