can I upgrade from Mojave 10.14.6 to Monterey 12.2?

Yes GCI_Digital, you can upgrade directly to Mac OS 12.2:

"If you're using macOS Mojave or later, you can get macOS Monterey via Software Update: Choose Apple menu  > System Preferences, then click Software Update.

Or use this link to open the macOS Monterey page on the App Store: Get macOS Monterey. Then click the Get button or iCloud download button"

officially you should be able to. but there have been reports here of some persons attempting to upgrade directly from mojave to monterey having the upgrade failing. so be ready for that eventuality. you may need to step up one macOS at a time all the way to monterey.

Here's the list on supported Macs than can run Monterey

https://support.apple.com/en-ph/HT212551

If your question is can you jump from Mojave to Monterey(provided your Mac is supported), follow these steps:

https://support.apple.com/en-us/HT212735