Remote Desktop Hacked?

I’d start with getting backups, as Time Machine doesn’t appear to be running and I don't see any scheduled backups. One of the very few ways to mark data as valuable is with scheduled backups. No backups means the data has no value.

Some of your Mac hardware could be failing (your battery is sketchy), or maybe you’ve got a corruption, or you’ve got other (probably software) issues.

Video or memory would be obvious possibilities for hardware issues described, though your aftermarket SSD is also slow, and is way too full. But before looking into that, (and given current backups of your data) I’d look into the software…

I’d start with removing AVG and MacKeeper. Removing those might require a re-install, as corruptions and issues caused by those sorts of products can be intractable. Add-on “security” apps, add-on VPN clients, and add-on “cleaner” apps can tend to degrade performance. Sometimes substantially. And while providing little value to you.

I’d also then remove the Google apps pending some other work, as those tend to consume prodigious resources doing who-knows-what, such as Chrome here nearly using half of your memory. Between all that add-on stuff and your presumably-needed Adobe CC apps, you’ve got ~zilch for memory left over, and ~zilch for free storage.

Running right near memory or near storage capacity gets slow.

TL;DR: insufficient free storage, far too much memory usage, problematic and unnecessary add-ons, bad battery, potentially other issues, and no backups.

The only remaining overt issues are the lack of TRIM, and the seeming lack of scheduled backups.

Check with Samsung about that setting, and about the current SSD firmware.

Set up Time Machine or some other scheduled backup, if the data stored here has any value to you.

Then restart through Safe Mode to rebuild caching, and re-test with screen sharing.