Hi Kelly,
2 weeks ago I took my 4th defective iPhone 4 to the genius bar here and they were simply at a loss as to why me and so many others have come in to their store with this issue. They offered to replace it again...with another refurbished/service phone. I denied the offer because I felt at the time that maybe...just maybe it was the service phones that were having the issue.
I left the store, called Apple's corporate number in Cupertino and the receptionist connected me to a person who placed an order and sent me a brand new phone. I took the phone in the sealed box to the Apple store with my Macbook Pro and said "here you go, you set it up". They did, it failed in front of them. They did a DFU?? and full restore on another computer of theirs....it failed.
Slide to unlock failures are a BIG problem that I believe ALL iPhones suffer from however I think many users might think they just didn't swipe their finger correctly and try again..and again until it opens.
Another "new" problem I've just encountered is in composing texts. If I go to contacts>Text Message> the contacts name does not appear in the To: line OR If I pick a contact to text it brings up the previous person I texted. This is really bad!!!
So in closing, the iPhone 5 best blow my mind with innovation and reliability.