Thanks everyone for your feedback (especially Servant of cats, as your name indicates we have something in common ;-)!
Selling my four LaCie 2Big Dock 20TB hard drives (80TB in total) and replacing them with a single bay/array that holds say 12 internal hard drives à 10TB (120TB in total) could of course be an appealing option to adding another two LaCie 20TB drives to my current four — provided of course that I really can daisy-chain all six to one of the iMac TB3 ports (which given the answers below I'm not yet completely sure I can do; someone mentioned a limit of 5 units, someone mentioned up to 6 units)?
The advantage with an additional two LaCie drives is that the setup with four has worked fine for me in terms of noise (they are not silent but at least fairly quiet; I have them in an open cupboard next to my computer desk), and it will be easier logistically to add two rather than first sell all four I have now and then purchase a bay/array setup to replace them with.
The advantage with switching to a bay/array setup is that I will have only one single unit connected to the iMac TB3 port, and anytime I need to up the ante storage-wise, I can easily replace one or more of the 10TB drives to a bigger size (I have seen there are now 20TB drives available). I am actually leaning towards this solution as I have the means for doing this, but my concern then is if a bay/array with 12 x 10TB drives will be as quiet as six separate LaCie 20TB units? Again, I have them just beside me, so noise level is a concerning issue. Has anyone here had any experience with such bay/array setups, or have information about their noise level compared to several separate drives?
Thanks in advance!
PS! I will look into the OWC bays mentioned; what I had otherwise found before is this bay from Synology:
https://www.proshop.se/Datalagring/Synology-DX1215II/2973828
This however doesn't seem to have a TB3/USB-C port, but rather something called "InfiniBand", which if I understand correctly should instead be connected to the iMac EtherNet port??