Definitely the old Apple KB, using a new-ish Microsoft KB, I get straight into safe mode and all looks a lot better.
Diagnostics from EtreCheck show that Major issue is auto-updates and security updates are disable, which I did deliberately in safe mode, but re enabled them now. Nothing else apart form identifying that the machine in in Safe mode.
Minor issue are the residue of Avast antivirus is running in the background, this was installed when I first got the mac mini, but replaced with McAfee. This has now been cleaned and no longer exists.
USB stuff
It has also picked up the Microsoft keyboard, which appear to be OK, along with the wireless Logitec trackball mouse I use. Also my old Thunderbolt screen
Network all looks fine.
System
macOS Monterey 12.7.4 (just updated)
Safe Mode Enabled.
HDD/Fusion = 60% used
Physical RAM = 8GB
RAM used = 2.6GB
Available = 5.4GM
CPU Usage Snapshot
System = 6%
User = 3%
Idle = 91%
Snapshot of the Apps installed and when show all that I use, plus a couple of old Apps I no longer need, so will remove those.
System and User Launch Daemons and Agents have no major issues, only a couple of disabled objects from those obsolete apps, now cleared.
The sys libs look ok as well, no issues.
In short, since changing the keyboard and clearing a couple of the obsolete things seem to be functioning very well.
Thanks for all you help, I think I can sort everything else from here.
May I say that, as a semi-retired Lead Systems Engineer, I very much appreciate the time and trouble people have gone to when someone calls for help!
Keep up the good work!
Thanks