The report does not document a drive problem.
Your Apple Fusion (hybrid) drive is running within the nominals for that drive config and is too fast to be your problem. Were it a mech-only system—evenm a mecha t 100% fundtion—max possible speeds are under 200MB/sec which WOULD feel slow. Your drive is not the issue.
The report DOES document this bit of nastiness:
Top Processes Snapshot by CPU:
Process (count) CPU (Source - Location)
com.apple.MobileSoftwareUpdate.UpdateBrainService 45.94 % ⚠️ (Not signed -/private/var/db/com.apple.xpc.roleaccountd.staging/exec/16777226.72828767.xpc/Contents/MacOS)
Anything eating up nearly HALF your processing capacity WILL slow the computer. That process appears to be part of the update system. You can find a lot by web-searching for
com.apple.MobileSoftwareUpdate.UpdateBrainService
The upshot is that it is part of the post-Catalina system update system that continues to do some work after the update is shown as installed. There are numerous reports that goes away after it finishes it housekeeping but could be 30 mins to aon hour. If it is "stuck," you can try a reboot and, that failing, a Safe Mode boot.
I'd run another Etrecheck report and see if that process is still being the fat hog at the trough.