USB is still problematic, I have problems with mouse, screen, drive, hub and so on.

Ok drive space has been a problem I agree, unfortunately it's not upgradable. I keep on clearing it but my docker containers and postgres dbs are just getting larger. I keep on flushing all unused images but still my docker vm is huge. I can uninstall things I am currently not using, thanks.

I did migrate, but just using the setup wizard not a time machine restore, hmmm.

Yes I have some USB2 buses and some USB3 busses. I don't use USB2 on USB3 busses, but my KVM only supports USB2.

Thanks this helps.

Cleaning up the drive helped a lot, but this morning the problem came back. It was working all afternoon just fine. It seems to be caused by Timemachine kicking in and trying to do a backup this time. It seems whenever any USB connection needs a lot of throughput something is flaking out. Sometimes it's audio, sometimes it's drive access. Then the computer disconnects all USB devices, waits a few seconds to reconnect them. I am not seeing anything interesting inside of the console, but probably because I don't know what to look for.

Ugh I am now also getting and error saying "USB Accessories Disabled" Unplug the accessory using too much power. This error is not possible, the device only has a single USB connection which is supplying the power and therefore the USB is also not actually disabled since I am using that connection. Hmmm, oh well, maybe it will just disappear in a new OS upgrade. These things definitely have come and gone, but every time they get more severe.

I suppose it's possible, except that there is only a single device connected to the Mac which is the TB3. In addition the TB3 connection is what's supplying power to the Mac in the first place. The only thing I could think of is that TB3 is an older device and the Mac might be pulling more power than advertised by TB3 to supply causing everything to reset. Since the Mac is fully charged up I don't see why it would be pulling a full 100W just sitting there, but then the Mac would be the device using too much USB power? Confused.

Ugh, something happened yesterday and now I am having audio and mouse and screen issues again. It feels like a deja vue. All of the "recent improvements" seem to have been reverted. I will try to reboot and do some more investigation, but right now I am kind of dead in the water again, disk drives disconnecting, audio not working and mouse/keyboard disconnecting randomly for seconds at a time. Was there an upgrade pushed?

Ok yea all day it's been hounding me. Same problem I began the thread with. USB is not reliably at all anymore. Keyboard has gaps when it doesn't work, Mouse has gaps, Audio works one direction, then the other and then never, sometimes it plays back a whole segment of audio really fast. My drives connect and disconnect randomly. Screens don't always sync. Even rebooted. This feels just like it did before I upgraded to Sequoia :(. There are some sections during the day where it all works without touching or changing anything, but then the problem returns. This time mds kicked in at 70% and took everything down, it's kind of random though and makes no immediate sense.

I am already on 15.0.1 (24A348) in case anyone is interested.

etrecheck sounds pretty good but it's not an apple tool and doesn't have the privacy page where they say it should be. How can I trust it?

I attached two files one connected and one disconnected

The original install was probably done a few Intel MBP's ago or maybe even and old MacPro, probably Lion or before.

I think it's actually mds. Both mds and the kernel are at high CPU and the rest of the system is resetting all the time.

It's a full thunderbolt 3 USB-C connection with PD. There is a TB4 which has thunderbolt 4 and a tiny bit more power, but this has enough power for most laptops including the current M2's.