Your PreSonus StudioLive 32S Mixer is a USB device and should not need any drivers on Mac systems.
What you may need to do after connecting via USB is to set it as your output audio device in Audio MDI Setup, which is in your /Applications/Utilities folder.
You would not use the mixer's TAPE channel because that is an analog line-level input, not USB. Of course, if you wanted to, you could connect the headphone out of your Mac to a line input on your mixer. But I do not recommend that method.
For an expensive mixer, the 32S documentation leaves a lot to be desired especially regarding USB input.