TimDanaher wrote:
Video Toolbox is Apple’s own codecs for HEVC (x.265). Handbrake does use FFmpeg, except if you choose the Video Toolbox option to get x.265 encoding. Then it uses Apple’s own codecs.
OK.
You have quite a number of 3rd party system modification apps. Several of those are firmly "grey market". Avoid anything that provides "clean-up" or "security" services.
The iSubtitle app has actually been crashing quite regularly. I don't know to what extent some of these apps modify system settings. It might be easier to erase the hard drive and reinstall the operating system. Then be much more cautious about 3rd party software.
Something like Handbrake might have an internal log that could give you more information about the problem.
Since these are mostly just apps, you can try creating a new user account on your machine and try it there. If it works, then the problem is confined to your user account. That might make it easier to correct. But if it happens in a new account, then the problem lies at the system level. If you can't track it down with log files, you'll have to wipe and reinstall.
The only app that still shows up on your EtreCheck report from "a few weeks ago" is Splashtop Streamer. That could be the cause. You could try uninstalling that app and see if it helps.