Yup. My Iphone 4S 32 GIG on TELUS does this. When I make some calls, the call will connect and timer will start... but I can't hear the other person, and they can't hear me. They eventually hang up, ending the call. Other times, I call and I can hear the other person.. but they can't hear me. Atleast not until I do the SPEAKER button trick. Where you turn on speaker phone, then turn it back off. Going into speakerphone enables the mic, and then exiting speakerphone keeps the mic on.. RARELY, I can make a completely normal call.. but not often. This happened since day 1, right out of the box. Awesome product there Apple. I greatly regret buying my first Iphone. Bought this phone at a Telus store, not Apple... so I took it back today and they are mailing it out to head Telus I suppose, to get it checked for problems. In which case if they can replicate this problem, I'll get a replacement. If they can't find a problem, then I guess I'll have a phone that works 'sometimes'. It almost feels better having no phone at all, but sadly I'll still get that bill in the mail at the end of the month, despite being robbed of my Iphone due to a stupid Apple issue. Thanks for nothing, RIM. Oops, I mean Apple... or, what? Maybe in time. :B