My V325 is now syncing perfectly with iCal and Address Book (PowerBook 15" 1.5GHz, 10.4.6). I had the common time-shift problem where events originating in iCal were all off by 4 hours on my phone. I fixed this by going into the iSync configuration for my V325, clicking on the "More Options..." button, and setting the time zone to GMT (Reykjavik, Iceland). I assume that this would fix the time-shift problem regardless of the time zone that your system is set to.
This made my day. I just got the V325 and so far am quite pleased with it. Also very pleased that it sycns (tho doesn't charge) over any plain old mini-USB cable (I used the one that came with one of my old digital cameras).