Do you start getting the noise right upon getting the replacement or does it take a couple of days? Mine was fine for the first 2.5 days then started up...At least I think so...It's possible that it took me 3 days to register the sound as a problem but I'd be surprised.
The specific direction from the Senior Advisor at Apple was as follows:
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I wanted to update you on the case. I forwarded your information to our Engineering team to ensure they were aware of the issue. They have let me know that units exhibiting the issue have recently been collected to further investigate, and they recommend going forward with normal repair or replacement routes.
You shouldn't have any trouble with getting the unit replaced, if that is your preference. Let me know if you have any questions or concerns.
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This is my first time having to deal with this on any Apple device so I don't know how the support bureaucracy works over there but it seems to me that something like this will eventually be recognized as a hardware defect and corrected via recall or at least return-able outside of the initial return window. Just make sure to leave a thorough paper trail of defect reports with support and keep track of your case numbers.
I scoured for people reporting this and am not coming up with that many though, so the fact that you have now gone through 3 with defects leads me to believe that either this is being very under-reported or you need to avoid Vegas. Still haven't seen any reports of this happening on non-Fusion drive systems... Anyone?