Until Epson and Apple get Epson Scan working again I have started using a workaround. The process of installing Epson Scan is detailed below. This workaround allows me to only scan using Epson Scan on my Epson 4490 scanner. Use at your own discretion. I am not sure the shut down & power up sequence in steps 06 & 09 are absolutely necessary but the procedure did work for me.
Epson 4490 - Procedure To Install Epson Scan into Applications Folder Of OSX Mavericks
01 Ensure operation is from a User Account with administrator privileges
02 Turn off Gatekeeper (System Preferences / Security / Privacy / Click lock . . / Allow apps . . .: Anywhere)
03 Shut Down Macintosh
04 Delete scanner files for Image Capture
04a Make OSX blind to scanner to avoid an “in use” message
04a1 Power off scanner
04a2 Disconnect USB network cable from scanner
04b Power Up Macintosh into a User Account with Administrator privileges
04c Move to Trash “EPSON Scanner” at OSX / Library / Image Capture / Devices /
05 Install “Epson Scan” (ES) into Application folder by launching "epson13680.dmg"
05a Epson Support site identifies this .dmg for OSX 10.6.x
05b Scanner Driver and EPSON Scan Utility v3.07A
05b1 EPSON Scan Utility and Universal Binary Scanner Driver (TWAIN) v3.07A.
http://www.epson.com/cgi-bin/Store/support/supDetail.jsp?oid=58611&infoType=Down loads&platform=OSF_M_X6
06 Shut Down Macintosh
07 Reconnect USB network cable to scanner
08 Power Up scanner
09 Power Up Macintosh
10 Return Gatekeeper to original settings
10a System Preferences / Security / Privacy / Click lock . . . / Reinstate previous setting
11 Exercise Epson Scan in Applications folder for scanning
12 If not ok move “EPSON Scanner” from Trash back to original location