Hit the issue after installing Mavericks. Actually I had it REALLY BAD. To the point where it even was walking me through the setup assistant - that was scary.
More importantly it was crashing SO much I couldn't even open a finder window to remove stuff.
First thing I did I was disable google drive (was installed but never used it). Didn't fix it.
Booted into safe mode (which made the whole system work just fine), and went through and pulled out the finder plist. Also removed stuff from startup window in System prefs. Booted back to normal: still busted.
Noticed there were a few MacAppStore apps still booting and started closing them. When I quit "Price Drop Monitor" (an app for tracking Amazon price drops) and suddenly the crash loop stopped.
Thought it was totally fixed, but did get a bunch of crashes early this morning while showering, but the loop stopped before I noticed and seemed to be fine. So I went in and deleted all files in the Library/LaunchAgents, Library/LaunchDaemons and Library/StartupItems folders.
So far everything seems fine. But holy crap was that not a great first run experience. I just got a new rMBP which is running Mavericks just fine. But if this had been my only system I'd have been pretty crazy. Not to mention some of the crappier aspects of Mavericks such as the loss of 3rd-party plugin support in Quicktime.