I've got to agree with everything in the above comment from @ "pattiharrington". I've got exactly the same issues.
I did all the terminal sudo and re-install from earlier version of iTunes - nada, zip, zilch, zero.
Does no one from Apple Tech Support actually read, and/or take any notice of the posts here.
And it's not just iTunes - the whole shebang is sluggish. Oh, yeah they gave us a redesigned spinning ball to keep us amused while some one comes up with a fix. Well I, for one, am not amused - I've just invested in a Retina 5K iMac with 32GB RAM and first thing it wanted to do when plugged in was upgrade the OS from Yosemite to El Capitan, with no way back, and which has left it running like a sloth. I now have a very expensive, but elegant paperweight! I have been using Apple equipment since the Mac Plus, but this, it seems is about has bad as it gets.
If I had really wanted a useless trinket, maybe I should have simply bought an iPhone and a watch!