I am one of the first reporters of this problem. My iPad Pro 10.5" 256GB has still iOS 10.3.3 on it. I also had this problem (unresponsive touch screen), 4 or 5 times during the first two weeks. I perform soft-reset to fix this issue every time. One day later after this issue occured, another issue popped up. Second issue was: iPad Pro did not wake up from sleep. Soft-Reset also fixed this issue temporary. After that, I decided to do a Hard-Reset by DFU mode by using iTunes on my Mac. After Hard-Reset, I did not restore from backup, instead I setup iPad Pro as a new device, and manually download apps. Next day after this, frozen touch screen issue happened one more time. Since that time (almost two months), this issue has never happened again. But few days ago after two months, after an intensive usage, frozen touchscreen issue occurred again. But this time, I clicked Sleep/Wake button once, and touchscreen was back to normal, this time I did not need to do a Soft-Reset. After next day of this issue, my iPad Pro did not wake up from sleep again, this time I held down sleep/wake button for few seconds until Apple logo appeared, and iPad Pro was back to normal again. This is my experience, using iPad Pro last 2.5 months. I started believing that, it may be bad batch of products. I am seriously considering to replace this iPad Pro at Apple Store, if I can.