Maybe I have found some clues...
Attached you'll find my network configuration.
The problem has begun with my wife's new iPhone SE, iOS 11.3
In our house we only use the 5ghz band due to the incredible number of interfering surrounding 2.4 ghz networks (54...).
For the same reason I had to create a completely wired Apple routers network, as showed in the picture, with the exception of an old Airport Express used as a wifi extender in my son's bedroom.
Using Ookla the "normal" attained speeds are: DL 94 Mbps / UL 48 Mbps.
Theese speeds are constant over many iOS devices in any angle of the house: iPad, iPad Pro, iPhone 6S, all using iOS 11.3 (same speeds are obtained by non-apple devices, wired and wireless).
With the notable exception of the new iPhone SE.
BUT it depends on the "kind" of Apple router to which it's connected: the Time Capsule and the Airport Extreme are fine, I can get the max speed using my wife's phone.
But when it is connected to the two wired Airport Express I can get just one third of the max speed in DL, being the UL speed optimal. And when it's connected to the old Airport Express...well...much slower
This happens ONLY using the iPhone SE
I came to the conclusion that we are considering at least three variables: the device operating system (iOS version) the router chipset (BTW all my routers have the latest firmware) and the device chipset.
Hope it helps!