Hi everyone,
I think I might have found a solution to my freeze problem! Found a hint on another website, tried something and now I have has no freezes for the whole day in spite of heavy workload and also provoking situations which caused freezes or a crash before. So keep fingers crossed! If it fails again, I will let you know.
Here comes my configuration, symptoms, and the solution:
iMac 27", early 2012, 32 GB, 3TB Fusion Drive, two supplementary non-Apple displays, lots of periphery
Freezes with no clearly visible pattern, between 10 and 50 secs, often combined with strange HD sounds, which already made me think my HD is going to die... often several times an hour. Crashes more than twice a day - all of this very annoying, specially when doing interview recordings over the internet.
The only discernible pattern was linked to graphic: videos, websites on safari with a lot of moving parts, Adobe Audition edition, where the wave display moves a lot, and similar
This made me follow a hint related to the Graphic cards driver! I have Nvidia 1 meg GC - the one that was originally built into my iMac.
SO I UPDATED THE DRIVER THAT CAME WITH OSX 10.13 WITH THE LATEST ONE I FOUND HERE:
http://www.macvidcards.com/drivers.html
This also installs a new item in the System Preferences, where you can chose between your new Nvidia Driver and the OSX one. I kept the new Nvidia and that stopped the freeze problem - well at least so far, but as I said, never had a whole day without problems before. And it sounds somehow logic that the problem relates to a Graphic card.
Hope it solves your headache too, let me know!